.
Oxycodone is a narcotic analgesic used to relieve moderate to severe pain. Oxycodone is available in combination products.
Interactions with Foods and Other Compounds
Food
Oxycodone may cause gastrointestinal (GI) upset. Oxycodone-containing products may be taken
with food to reduce or prevent GI upset.1 A common side effect of narcotic
analgesics is constipation.2 Increasing
dietary fiber (especially vegetables and
whole-grain foods) and water intake can ease constipation.
Alcohol
Oxycodone may cause drowsiness, dizziness, or blurred vision. Alcohol may intensify these
effects and increase the risk of accidental injury.3 To prevent problems, people
taking oxycodone should avoid alcohol.
Summary of Interactions for Oxycodone
| Depletion or interference | None known |
|---|---|
| Adverse interaction | None known |
| Side effect reduction/prevention | None known |
| Supportive interaction | None known |
| Reduced drug absorption/bioavailability | None known |
For the convenience of the reader, the information in the summary is categorized as follows: “Depletion or interference” indicates the drug may deplete or interfere with the absorption or function of the supplement or herb. “Adverse interaction” indicates that the supplement or herb used together with the drug may result in undesirable effects. “Side effect reduction/prevention” indicates the supplement or herb may reduce the likelihood and/or severity of a potential side effect caused by the drug. “Supportive interaction” indicates the supplement or herb may support or aid the function of the drug. “Reduced drug absorption/bioavailability” indicates that the supplement or herb may decrease the absorption and/or activity of the drug in the body. An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
References:
1. Threlkeld DS, ed. Central Nervous System Drugs, Narcotic Agonist Analgesics. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1990, 242–3v.
2. Threlkeld DS, ed. Central Nervous System Drugs, Narcotic Agonist Analgesics. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1990, 242–3v.
3. Threlkeld DS, ed. Central Nervous System Drugs, Narcotic Agonist Analgesics. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1990, 242–3v.
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