.
Zolmitriptan is used to treat acute attacks of migraine headache and is in a class of drugs known as serotonin antagonists. There are currently no reported nutrient or herb interactions involving zolmitriptan.
Interactions with Dietary Supplements
5-Hydroxytryptophan
(5-HTP)
Zolmitriptan works by stimulating serotonin receptors in the brain. 5-HTP and L-tryptophan are
converted to serotonin in the brain, and taking them with zolmitriptan could increase
zolmitriptan-induced side effects. However, no interactions have yet been reported with
zolmitriptan and 5-HTP or L-tryptophan.
Summary of Interactions for Zolmitriptan
| Depletion or interference | None known |
|---|---|
| Adverse interaction | 5-Hydroxytryptophan
(5-HTP)* L-tryptophan* |
| Side effect reduction/prevention | None known |
| Supportive interaction | None known |
| Reduced drug absorption/bioavailability | None known |
For the convenience of the reader, the information in the summary is categorized as follows: “Depletion or interference” indicates the drug may deplete or interfere with the absorption or function of the supplement or herb. “Adverse interaction” indicates that the supplement or herb used together with the drug may result in undesirable effects. “Side effect reduction/prevention” indicates the supplement or herb may reduce the likelihood and/or severity of a potential side effect caused by the drug. “Supportive interaction” indicates the supplement or herb may support or aid the function of the drug. “Reduced drug absorption/bioavailability” indicates that the supplement or herb may decrease the absorption and/or activity of the drug in the body. An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
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